The Circadian Approach to Skin Health Through Targeted Nutrition

A comprehensive two-step supplement system designed by Dr David Jack provides targeted nutritional support aligned with the body's natural 24-hour rhythms. Morning support focuses on antioxidant protection and energy, whilst evening formulation promotes relaxation and overnight repair.

Nutritional science continues to reveal the profound connection between internal health and external skin appearance. Dr David Jack, a renowned expert in the field, has developed a comprehensive approach to skincare that moves beyond topical treatments and focuses on the body’s natural circadian rhythms.

The AM | PM Supplement System represents a sophisticated two-step nutritional protocol designed to support skin health, energy levels and overnight recovery. This innovative approach recognises that skin health cannot be achieved through external solutions alone; rather, it requires comprehensive internal support across the full 24-hour cycle.

Morning Support: Antioxidant Protection and Cellular Energy

The morning formulation delivers a carefully selected blend of antioxidants, vitamins and cellular nutrients specifically chosen to support energy production whilst defending against environmental stressors. The system’s cornerstone ingredient is SkinAx2®, a patented botanical complex that combines grape seed extract with French melon extract. This combination provides superoxide dismutase (SOD), which reinforces the body’s natural antioxidant defence mechanisms.

Complementing this foundation is Astareal® astaxanthin, recognised as one of the most potent marine antioxidants available. This ingredient specifically supports skin resilience and provides protection against oxidative damage associated with premature skin ageing. The addition of vitamins C, D and E ensures comprehensive support for collagen formation, immune function and cellular protection across multiple systems.

Cellular energy production receives targeted support through coenzyme Q10 and alpha-lipoic acid, both critical cofactors in mitochondrial function. Polypodium leucotomos extract, derived from a fern species with well-established photoprotective properties, provides systemic UV protection that complements topical sunscreens. Scientific research demonstrates that this botanical helps reduce UV-induced oxidative damage, supports DNA protection within skin cells and may significantly limit inflammation triggered by sun exposure.

Evening Recovery: Sleep Quality and Overnight Repair

The evening formulation addresses the body’s most critical repair window: sleep and recovery. Ashwagandha, an adaptogenic herb with centuries of traditional use, helps support relaxation and assists the body in managing its stress response. This is particularly relevant to skin health, as chronic stress directly undermines skin function and appearance.

L-tryptophan serves as a precursor for both serotonin and melatonin production, supporting healthy sleep cycles and mood regulation -both essential foundations for optimal skin health. Magnesium contributes to nervous system balance and muscular relaxation, allowing the body to properly transition into restorative sleep stages. Supporting ingredients including quercetin, grape seed extract and lemon balm provide additional antioxidant support whilst promoting the calm and relaxation necessary for deep, restorative rest.

A Circadian Approach to Skincare

What distinguishes this system is its recognition of the body’s natural circadian rhythms. Rather than providing a single supplement throughout the day, the two-step protocol aligns with the body’s biological patterns: providing active antioxidant and protective support during daylight hours when environmental stressors are at their peak, and shifting toward relaxation and repair support during evening hours when the body naturally focuses on renewal.

This sophisticated approach to internal skin health represents a significant evolution in how we think about skincare. The system provides flexibility for those seeking comprehensive support for skin health, energy and overnight recovery.

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